Monday 1 June 2009

Inclusion of garlic in daily dietary intake will prevent cataract

By Syed Akbar
Hyderabad: Inclusion of garlic in daily dietary intake will prevent cataract, particularly the one related to diabetes.
A joint study by the department of zoology of Osmania University and the Centre for Cellular and Molecular Biology revealed that garlic had properties that would prevent the onset of cataract. The effect of garlic on cataract was more pronounced in the case of diabetics.
Thus far there's no potent therapeutic agent that could prevent or control the lens from opacification. Metabolic intervention through natural dietary ingredients like garlic will help in better management of the problem.
T Naga Raju and V Rajani Kanth of Osmania University and K Lavanya of CCMB carried out the research on rats.
"The ability of methanolic garlic extract in scavenging the transition metal ion-generated hydrogen peroxide reflected its antioxidant activity and indicated that it can prevent protein modifications mediated through metal-catalysed reactions in cataractous lenses," they said.
Garlic administration was found to normalise the glucose levels in a dose-dependent manner, suggesting its hypoglycemic (lower sugar levels) potential. The glycemic-mediated oxidative damage was countered by the garlic extract by delaying the progression of cataract.
Glycemic-induced stress is a major culprit contributing to oxidative insult that has far-reaching effects in diabetic cataract world-wide. And garlic being an antioxidant, it checks the growth of cataract.

Sunday 26 April 2009

Take cloves to beat stress, keep away heart attacks


2009
By Syed Akbar
We all know that laung or clove is good for teeth. Clove oil helps in fighting tooth decay and gives relief from toothache. But now Indian scientists have come out with a study that tells us that clove (Eugenia caryophyllus) is the best stress buster and keeps away heart problems. Stress is emerging as the major killer in the world and clove is the simplest remedy to the problem. Since stress and heart ailments are related, by taking cloves regularly one will not only beat the stress but also fights heart attacks.

Clove contains a special substance called hydro alcohol and this substance is known to give relief from stress. The scientific team studied the anti-stress effect of hydro-alcoholic extract of clove by evaluating it on cold restraint induced gastric ulcers, sound stress induced biochemical changes and anoxic stress induced convulsions.

As part of the research project the extract from the clove was given orally twice daily to mice. The first dose was of 100 mg/kg while the second dose was of 200 mg/kg. The team used zeetress, a known anti-stress formulation as the standard drug.

The scientific team comprised Anand Kumar Singh, Sunil S Dhamanigi and Mohammed Asad of Krupanidhi College of Pharmacy, Bengaluru. The researchers found that both the doses of clove extract showed good anti-stress effect in all the tested models. The clove extract reduced the development of cold restraint induced gastric ulcers and prevented the biochemical changes induced by sound stress such as increase in plasma levels of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, glucose, cholesterol and corticosterone.

"Stress is a common phenomenon that is experienced by every individual. When stress becomes extreme, it is harmful for the body and, hence, needs to be treated. Stress is involved in the pathogenesis of a variety of diseases that includes psychiatric disorders such as depression and anxiety, immunosuppression, endocrine disorders including diabetes mellitus, male impotence, cognitive dysfunction, peptic ulcer, hypertension and ulcerative colitis," the study pointed out saying that clove, is one of the natural stress busters.

For the purpose of the study, the team selected albino Wistar rats weighing between 175 and 250 gm and Swiss albino mice weighing 25 to 40 gm. The experiment continued for 14 days. Stress was induced in the mice through chemicals and later clove extract was administered to them.

The team showed that hydro-alcoholic extract of clove possesses significant anti-stress activity. "The effect of clove may be due to its effect on the central nervous system or endocrines and it may also be due to its antioxidant effect as anti-oxidants are known to prevent stress induced damage due to generation of
free radicals," the study said.

The clove gets its medicinal properties mainly because of the presence of volatile oils like eugenol. The team however noted that the exact mechanism by which clove produces its anti-stress activity cannot be explained with the data collected during the study. "We speculated that the antioxidant effect of the clove buds might contribute at least in part to its anti-stress activity," the scientists said.

So, the next time you come across spicy food, do not complain. Ensure that the "spicy food" has a good number of cloves too. This will bust your stress, whether it is work-related or due to domestic problems.